C112. Lee SY, Jeong MH, Rhee JA, Choi JS, Hwang SH, Ko JS, Lee MG, Sim DS, Park KH, Yoon NS, Yoon HJ, Kim KH, Hong YJ, Kim JH, Ahn Y, Cho JG, Park JC and Kang JC; Clinical Outcomes of Persistent Smoking in Patients with Acute Myocardial Infarction Who Underwent Percutaneous Coronary Intervention. Korean J Med. 2011;80(5)562-570.
(Abstract)
Background/Aims: To analyze the clinical effects of continuing to smoke in patients with acute myocardial infarction (AMI), clinical outcomes of those continuing or ceasing smoking were compared.
Methods: In total, 498 patients with AMI who underwent percutaneous coronary intervention (PCI) from January to December 2007 were enrolled. Of these patients, 407 (63.9 ± 11.9 years, males 70%) with 1-year follow-ups were analyzed. Based on risk factors for smoking, patients were divided into two groups: Group I (smokers, n = 164, 57.9 ± 11.2 years) and Group II (nonsmokers, n = 243, 68.0 ± 10.6 years). Additionally, Group I patients were subdivided by cessation of smoking after discharge: Group IA (current smokers, n = 95, 56.8 ± 10.5 years) and IB (past smokers, n = 69, 59.4 ± 12.0 years). Clinical characteristics, coronary angiographic and procedural findings, and 1year major adverse cardiac events (MACE) were analyzed.
Results: During the 1-year follow-up period, MACE developed in 112 patients (27.6%) and death in 42 patients (10.3%). In terms of smoking habits at admission, there was no significant difference in the 1-year MACE between current smokers (Group I) and nonsmokers (Group II). In the subgroup analysis, there were no significant difference in clinical characteristics between Groups I Α and IΒ. Mortality was significantly higher in Group IA than in Group IB during the 1-year clinical follow-up (11% vs. 0%; p = 0.005).
Conclusions: Of the AMI patients who underwent PCI, mortality was significantly higher in current smokers than in past smokers after PCI.
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DATE : 16-03-14 14:05
HIT : 2,343
