C113. Kee WJ, Jeong MH, Jang SY, Lee MG, Park KH, Sim DS, Hong YJ, Kim JH, Ahn Y, Kang JC; Very Late Stent Thrombosis due to Neointimal Rupture After Paclitaxel-Eluting Stent Implantation. Korean Circ J. 2011:41;(12)754-758.
(Abstract)
We report our experience of very late stent thrombosis (VLST) in a young male patient who underwent implantation of two paclitaxel-eluting stents (PES) six years ago. The patient was compliant with standard dual antiplatelet therapy, but he pre\-sented with acute myocardial infarction which was associated with VLST. Intravascular ultrasound showed neointimal rup-ture with thrombus within the PES implanted in the right coronary artery. The lesion was successfully treated with balloon angioplasty without complications, however he was found to be hyporesponsive to clopidogrel when tested for adenosine diphosphate-induced platelet aggregation. The patient was discharged after uneventful recovery with triple anti-platelet thera\-py using aspirin, clopidogrel and cilostazol. To the best of our knowledge, a time interval of 2,223 days is the longest reported time interval between PES deployment and VLST occurrence. VLST may indeed occur in clinically stable patients, as multi\-ple factors can influence the pathological mechanisms of VLST.
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