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논문번호 289
논문제목(영문) Two-year Outcomes between ST-elevation and Non-ST-Elevation Myocardial Infarction in Patients with Chronic Kidney Disease Undergoing Newer-Generation Drug-Eluting Stent Implantation.
국내외구분 국외 SCI여부 SCI(E)
연구책임자역할 공저자
주저자명 Kim YH
교신저자명 Kim YH
공동저자명 Her AY, Jeong MH, Kim BK, Hong SJ, Lee SJ, Ahn CM, Kim JS, Ko YG, Choi D, Hong MK, Jang Y
게제년월일 2022-03-01
ISSN 1522-1946
Impact Factor 2.3
학술지명 Catheter Cardiovasc Interv
서지사항 0집 / 99권 / 4호,   페이지(1022 - 1037)
요약초록문
(Abstract) 입력		 Background: We evaluated the 2-year clinical outcomes of ST-elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI) in patients with chronic kidney disease (CKD) who received newer-generation drug-eluting stents (DES).

Methods: Overall, 18,875 acute myocardial infarction patients were divided into two groups: CKD (STEMI, n = 1707; NSTEMI, n = 1648) and non-CKD (STEMI, n = 8660; NSTEMI, n = 6860). The occurrence of major adverse cardiac events (MACE), defined as all-cause death, recurrent myocardial infarction (re-MI), any repeat coronary revascularization, and definite or probable stent thrombosis (ST), was evaluated.

Results: After multivariable-adjusted analysis, in the CKD group, the MACE (adjusted hazard ratio [aHR]: 1.365, p = 0.004), all-cause death (aHR: 1.503, p = 0.004), noncardiac death (non-CD; aHR: 1.960, p = 0.004), and all-cause death or MI rates (aHR: 1.458, p = 0.002) were significantly higher in the NSTEMI group than in the STEMI group. In the non-CKD group, the non-CD rate (aHR: 1.78, p = 0.006) was also higher in the NSTEMI group. The CD, re-MI, any repeat revascularization, and ST rates were similar between groups. In the CKD group, from 6 months to 2 years after the index procedure, all-cause death, non-CD, and all-cause death or MI rates were significantly higher in the NSTEMI group than in the STEMI group. These results may be related to the higher non-CD rate in the NSTEMI group.

Conclusions: In the era of contemporary newer-generation DES, NSTEMI showed a relatively higher non-CD rate than STEMI in both CKD and non-CKD groups.
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