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논문번호 290
논문제목(영문) Effect of Wire Jailing at Side Branch in 1-Stent Strategy for Coronary Bifurcation Lesions.
국내외구분 국외 SCI여부 SCI(E)
연구책임자역할 공저자
주저자명 Choi YJ, Lee SJ
교신저자명 Kim BK
공동저자명 Hong SJ, Ahn CM, Kim JS, Gwon HC, Kim HS, Chun WJ, Hur SH, Nam CW, Han SH, Rha SW, Chae IH, Jeong JO, Heo JH, Yoon J, Lim DS, Park JS, Cha KS, Kim DI, Lee SY, Chang K, Hwang BH, Choi SY, Jeong MH, Choi KH, Song YB, Hong SJ, Doh JH, Koo BK, Hong MK, Jang Y
게제년월일 2022-02-28
ISSN 1936-8798
Impact Factor 11.3
학술지명 JACC Cardiovasc Interv
서지사항 0집 / 15권 / 4호,   페이지(443 - 455)
요약초록문
(Abstract) 입력		 Objectives: This study aimed to determine whether side branch (SB) wire jailing before main vessel (MV) stenting could prevent SB occlusion after the 1-stent strategy for bifurcation percutaneous coronary intervention.

Background: The benefits of SB wire jailing in the 1-stent strategy remain unclear.

Methods: From the COBIS (Coronary Bifurcation Stenting) III registry, 1,890 patients with bifurcation lesions who underwent the 1-stent strategy using second-generation drug-eluting stents were identified and classified into 2 groups according to the use of SB wire jailing: wire jailing (n = 819) and non-wire jailing (n = 1,071). The incidence of SB occlusion (Thrombolysis In Myocardial Infarction flow grade <3) and target lesion failure (cardiac death, myocardial infarction, or target lesion revascularization) was compared.

Results: The incidence of final SB occlusion was not significantly different between wire jailing (1.8%) vs non-wire jailing (2.9%; P = 0.182). However, wire jailing at the SB was a significant protective factor for SB occlusion after MV stenting on multivariate analysis and was significantly associated with a lower incidence of SB occlusion in patients with significant stenoses (≥60%) at the SB (5.1% vs 11.3%; odds ratio: 0.42; 95% CI: 0.19-0.89; P = 0.028) or MV (3.1% vs 6.2%; odds ratio: 0.49; 95% CI: 0.24-0.95; P = 0.039). During follow-up (median 52 months), the incidence of target lesion failure was not significantly different between wire jailing and non-wire jailing (7.6% vs 6.3%; P = 0.343).

Conclusions: During bifurcation percutaneous coronary intervention with the 1-stent strategy, wire jailing at the SB was associated with a lower rate of final SB occlusion following MV stenting in patients with severe stenoses at the SB or MV but not with overall bifurcation lesions. Long-term clinical outcomes were comparable between the 2 groups.
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