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논문번호 293
논문제목(영문) Safety and Efficacy of Contemporary Drug-Eluting Stents in Patients With ST-Segment Elevation Myocardial Infarction and a High Ischemic Risk.
국내외구분 국외 SCI여부 SCI(E)
연구책임자역할 교신저자
주저자명 Lee OH, Kim Y
교신저자명 Jeong MH
공동저자명 Son NH, Cho DK, Kim JS, Kim BK, Choi D, Hong MK, Jang Y
게제년월일 2022-05-23
ISSN 2297-055X
Impact Factor 3.6
학술지명 Front Cardiovasc Med
서지사항 0집 / 9권 / 0호,   페이지(880351 - 880351)
요약초록문
(Abstract) 입력		 Background: In patients with ST-elevation myocardial infarction (STEMI) with a high risk of ischemic events, the safety and efficacy of drug-eluting stent (DES) are unclear.

Methods: Based on the nationwide, multicenter, prospective registry, we selected 1,592 patients who underwent primary percutaneous coronary intervention (PCI) with everolimus-(EES) and zotarolimus-eluting stent (ZES) for STEMI with a high risk of an ischemic event. The occurrence of target lesion failure (TLF) for 3 years, defined as the composite of cardiac death, target vessel myocardial infarction (TV-MI), and ischemia-driven target lesion revascularization (ID-TLR), was evaluated.

Results: The prevalence of high ischemic risk features was observed in 43.4% (2,744/6,325) of overall patients with STEMI. Among them, a total of 1,078 and 514 patients were treated with EES and ZES, respectively. At 3 years, the risk of TLF was not significantly different between the two groups (p = 0.93). In addition, the incidence of cardiac death, TV-MI, ID-TLR, and definite/probable stent thrombosis (ST) were also not different between the two groups. Moreover, elderly patients (age > 75 years) and PCI for the left main disease were identified as independent predictors of TLF.

Conclusion: Implantation of EES or ZES provided comparable clinical outcomes in STEMI patients and high ischemic risks.

Keywords: ST-segment elevation myocardial infarction; drug-eluting stent; high risk factor; percutaneous coronary intervention (PCI); target lesion failure.
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