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논문번호 64
논문제목(영문) Impact of postprocedure minimum stent area on long-term results following abciximab-coated stent implantation: an intravascular ultrasound analysis.
국내외구분 국외 SCI여부 SCI(E)
연구책임자역할 교신저자
주저자명 Hong YJ
교신저자명 Jeong MH
공동저자명 Hong YJ, Jeong MH, Hwang SH, Yun NS, Lim SY, Lee SR, Hong SN, Kim KH, Park HW, Kim JH, Kim W, Ahn YK, Cho JG, Park JC, Kang JC;
게제년월일 2006-11-09
ISSN 0167-5273
Impact Factor 4.036
학술지명 International journal of cardiology
서지사항 0집 / 123권 / 1호,   페이지(23 - 28)
요약초록문
(Abstract) 입력		 BACKGROUND:
Smaller postprocedural minimum stent areas (MSA) measured by intravascular ultrasound (IVUS) have been associated with higher restenosis rates.
METHODS:
This was a single-center, prospective, randomized trial and we assessed the predictive value of MSA for long-term patency and the incidence and extent of incomplete stent apposition (ISA) following abciximab-coated stent (n=69) compared to bare metal stent (BMS) implantation (n=69). All patients underwent IVUS follow-up at 6 months.
RESULTS:
At follow-up coronary angiogram, the restenosis rate and late loss were 12%, 0.30+/-0.24 mm in abciximab-coated stent group and 29%, 0.68+/-0.36 mm in BMS group (p=0.011, 0.010, respectively). At follow-up IVUS, intrastent lumen area was significantly larger and intrastent neointimal hyperplasia area was significantly smaller in abciximab-coated stent group than those in BMS group (5.9+/-1.6 mm(2) vs. 4.5+/-1.7 mm(2), p=0.001, and 1.9+/-1.5 mm(2) vs. 3.3+/-1.9 mm(2), p<0.001, respectively). Target lesion revascularization occurred in 9%, 0%, and 0% in abciximab-coated stent group and 19%, 4%, and 1% in BMS group in lesions with a MSA <6.0 mm(2), from 6 to 7.5 mm(2), and >7.5 mm(2), respectively. Late-acquired ISA at follow-up was observed in 7 patients and there was no difference in the incidence of ISA between both groups [abciximab-coated stent: n=3 (4%) vs. BMS: n=4 (6%), p=0.698].
CONCLUSION:
Abciximab-coated stent reduced restenosis and had a considerably lower optimal MSA threshold compared to BMS and showed lower incidence of late-acquired ISA.
파일  C64.+Int+J+Cardiol.+2007;123(1)23-28..pdf (161.0K) DATE : 2021-05-21 16:47:04