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논문번호 205
논문제목(영문) Strategy for STEMI With Bifurcation Culprit Lesion Undergoing Primary PCI: The COBIS II Registry.
국내외구분 국외 SCI여부 SCI(E)
연구책임자역할 공저자
주저자명 Choi KH
교신저자명 Song YB, Jeong JO
공동저자명 Choi KH, Song YB, Jeong JO, Park TK, Lee JM, Yang JH, Hahn JY, Choi SH, Choi JH, Lee SH, Jeong MH, Koo BK, Kim HS, Yu CW, Rha SW, Jang Y, Yoon JH, Oh JH, Park JS, Gwon HC.
게제년월일 2018-02-20
ISSN 1885-5857
Impact Factor 4.485
학술지명 Revista española de cardiología
서지사항 0집 / 18권 / 0호,   페이지(30006 - 30009)
요약초록문
(Abstract) 입력		 INTRODUCTION AND OBJECTIVES:
There are limited data on the preferred treatment strategy in ST-segment elevation myocardial infarction (STEMI) patients with bifurcation lesions. This study aimed to compare clinical outcomes between 1-stent and 2-stent strategies in STEMI patients with bifurcation lesions undergoing primary percutaneous coronary intervention (PCI).

METHODS:
The COronary BIfurcation Stenting II is a retrospective multicenter registry of 2897 consecutive patients with bifurcation lesions undergoing PCI with drug-eluting stents from January 2003 through December 2009. Among the registered population, 367 (12.7%) patients had STEMI; of these, a 1-stent strategy was used in 304 patients and a 2-stent strategy in 63 patients; 77.1% of the patients received primary PCI with a first-generation drug-eluting stent. The inverse-probability-of-treatment-weighting method was used to adjust for confounding factors. The primary outcome was major adverse cardiovascular events (MACE), a composite of cardiac death, myocardial infarction, target lesion revascularization, and stent thrombosis.

RESULTS:
The median length of follow-up was 38 months. Postprocedural side branch diameter stenosis differed significantly between the 2 groups (1-stent vs 2-stent, 42.7% vs 9.7%; P < .001). After the performance of inverse-probability-of-treatment-weighting methods, the rate of MACE was significantly higher in the 2-stent group than in the 1-stent group (HR, 1.85; 95%CI, 1.19-2.87; P = .006), mainly driven by target lesion revascularization and stent thrombosis.

CONCLUSIONS:
In STEMI patients with bifurcation culprit lesions undergoing primary PCI, the 2-stent strategy had significantly higher rates of MACE than the 1-stent strategy, despite successful treatment of the side branch. However, this result should be interpreted with caution because this study does not reflect current practice.
파일  C 205 Treatment Strategy for STEMI With Bifurcation Culprit Lesion Undergoing Primary PCI.pdf (462.7K) DATE : 2018-05-28 14:53:25