임상

HOME > 연구실적 > 임상 > 논문
 
작성일 : 16-03-14 00:59
논문번호 108
논문제목(영문) Impact of intravascular ultrasound guidance on long-term clinical outcomes in patients treated with drug-eluting stent for bifurcation lesions: data from a Korean multicenter bifurcation registry.
국내외구분 국외 SCI여부 SCI(E)
연구책임자역할 공저자
주저자명 Kim JS
교신저자명 Hong MK
공동저자명 Kim JS, Hong MK, Ko YG, Choi D, Yoon JH, Choi SH, Hahn JY, Gwon HC, Jeong MH, Kim HS, Seong IW, Yang JY, Rha SW, Tahk SJ, Seung KB, Park SJ, Jang Y;
게제년월일 2010-10-04
ISSN 0002-8703
Impact Factor 4.463
학술지명 American heart journal
서지사항 0집 / 161권 / 1호,   페이지(180 - 187)
요약초록문
(Abstract) 입력
BACKGROUND:
although intravascular ultrasound (IVUS) has been widely used for complex lesions during coronary intervention, IVUS for stenting at bifurcation lesions has not been sufficiently assessed. The aim of this study was to investigate the impact of IVUS guidance on long-term clinical outcomes during drug-eluting stent (DES) implantation for bifurcation lesions.
METHODS:
the Korean multicenter bifurcation registry listed 1,668 patients with non-left main de novo bifurcation lesions who underwent DES implantation between January 2004 and June 2006. Using propensity score matching with clinical and angiographic characteristics, 487 patients with IVUS guidance and 487 patients with angiography guidance were selected. The long-term clinical outcomes were compared between the 2 groups.
RESULTS:
baseline clinical and angiographic characteristics were well matched and showed no significant differences between the 2 groups. Two-stent technique and final kissing ballooning angioplasty were more frequently performed in the IVUS-guided group. Maximal stent diameters at both the main vessel and the side branch were larger in the IVUS-guided group. Periprocedural creatine kinase-MB elevation (>3 times of upper normal limits) was frequently observed in the angiography-guided group. The incidence of death or myocardial infarction was significantly lower in the IVUS-guided group compared to the angiography-guided group (3.8% vs 7.8%, log rank test P = .03, hazard ratio 0.44, 95% CI 0.12-0.96, Cox model P = .04).
CONCLUSIONS:
intravascular ultrasound guidance during DES implantation at bifurcation lesions may be helpful to improve long-term clinical outcomes by reducing the occurrence of death or myocardial infarction.
파일  C108.+Am+Heart+J.+2011;161(1)180-187..pdf (215.6K) DATE : 2021-05-25 14:32:01