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논문번호 114
논문제목(영문) Drug-eluting vs. bare-metal stents for treatment of acute myocardial infarction with renal insufficiency. Results from Korea Acute Myocardial Infarction Registry.
국내외구분 국외 SCI여부 SCI(E)
연구책임자역할 공저자
주저자명 Bae EH
교신저자명 Kim SW
공동저자명 Bae EH, Lim SY, Choi YH, Suh SH, Cho KH, Choi JS, Kim CS, Park JW, Ma SK, Jeong MH, Kim SW;
게제년월일 2011-08-29
ISSN 1346-9843
Impact Factor 3.940
학술지명 Circulation journal
서지사항 0집 / 75권 / 12호,   페이지(2798 - 2804)
요약초록문
(Abstract) 입력		 Abstract:
BACKGROUND: Patients with chronic kidney disease have had conflicting results
between drug-eluting stents (DES) and bare-metal stents (BMS). The aim of the
present study was to determine whether DES is preferable for the treatment of
acute myocardial infarction (AMI) with renal insufficiency, and to elucidate the
impact of diabetes mellitus (DM) on outcomes of each stent.
METHODS AND RESULTS: As a part of the Korea Acute Myocardial Infarction Registry (KAMIR), 2,175 AMI patients with renal insufficiency (glomerular filtration rate <60ml/min) comprising 208 patients with BMS and 1,967 DES implantation were selected. Primary outcome was major adverse cardiac event (MACE), defined as a composite of mortality, nonfatal myocardial infarction, and target lesion revascularization. In the overall population, the MACE rate at 1 year was significantly higher in the BMS group than that of DES (44% vs. 26%, P<0.05), which was mainly due to death rather than repeat intervention (44% vs. 26%, P<0.05). In the diabetic group with DES implantation, the MACE rate was higher compared with the DES group without DM, mainly due to repeat intervention (5% vs.8%, P<0.05). CONCLUSIONS: In AMI patients with renal insufficiency, DES implantation exhibits a favorable 1-year clinical outcome than BMS implantation, and subgroup analysis for diabetic subjects showed worse outcomes in the DM group with implanted DES.
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