임상

HOME > 연구실적 > 임상 > 논문
 
작성일 : 16-03-14 01:23
논문번호 122
논문제목(영문) Comparison of drug-eluting versus bare-metal stent implantation in ST-elevation myocardial infarction patients with renal insufficiency: Results from the national registry in Korea.
국내외구분 국외 SCI여부 SCI(E)
연구책임자역할 공저자
주저자명 Kim KH
교신저자명 Kim HS
공동저자명 Kim KH, Koo BK, Min HS, Park SK, Kim CH, Park KW, Park BJ, Jeong MH, Cho MC, Lee SR, Chae SC, Seong IW, Choi DJ, Kim HS;
게제년월일 2010-09-05
ISSN 0167-5273
Impact Factor 4.036
학술지명 International journal of cardiology
서지사항 0집 / 154권 / 1호,   페이지(71 - 77)
요약초록문
(Abstract) 입력		 Introduction: It is unknown whether drug-eluting stents (DES), in comparison with bare-metal stents (BMS), improve clinical outcomes of ST-elevation myocardial infarction (STEMI) patients with renal insufficiency. We aimed to compare the clinical outcomes of BMS versus DES, as well as sirolimus-eluting stents (SES) versus paclitaxel-eluting stents (PES), in STEMI patients with renal insufficiency.
Methods: From the Korea Acute Myocardial Infarction Registry, 874 STEMI patients with renal insufficiency (glomerular filtration rate b60 ml/min) comprising 116 patientswithBMSand 758 patientswithDES (430 SES and328 PES) implantationwere selected. Major adverse cardiac events (MACE)within 1 year, defined as composite of all-cause mortality, nonfatalmyocardial infarction and target lesion revascularization were compared. In addition to multivariate adjusted analysis, propensity analysis for stent choice was performed.
Results: With a median follow-up of 342 days, 116 MACE occurred. MACE was more frequent in the BMS group than in the DES group before (HR [95% CI]=2.3 [1.3–3.8]) and after propensity scorematching (HR [95% CI]=2.0 [1.0–3.8]). The difference ofMACE wasmainly driven by a higher rate of target lesion revascularization rate in the BMS group. In comparison between SES and PES, there was no significant difference between the 2 groups in propensity score-matched populations (HR [95% CI]=0.7 [0.4–1.1]).
Conclusions: In STEMI patients with renal insufficiency, DES implantation exhibits a favorable 1 year clinical outcomes than BMS implantation, however, no difference was found between SES and PES.
파일  C122.+Int+J+Cardiol.+2012;154(1)71-77..pdf (403.6K) DATE : 2021-05-25 15:24:23