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논문번호 184
논문제목(영문) Two-Year Safety and Efficacy of Biodegradable Polymer Drug-Eluting Stent Versus Second-Generation Durable Polymer Drug-Eluting Stent in Patients With Acute Myocardial Infarction: Data from the Korea Acute Myocardial Infarction Registry (KAMIR).
국내외구분 국외 SCI여부 SCI
연구책임자역할 공저자
주저자명 Hur SH
교신저자명 Hur SH
공동저자명 Hur SH, Kim IC, Won KB, Cho YK, Yoon HJ, Nam CW, Kim KB, Kim MS, Park J, Rha SW, Chae SC, Kim YJ, Kim CJ, Cho MC, Jeong MH, Ahn YK, Kim HS, Ahn TH, Seung KB, Jang Y, Yoon JH, Seong IW, Hong TJ, Bae JH, Park SJ; KAMIR (Korea Acute Myocardial Infarction Re
게제년월일 2016-01-13
ISSN 0160-9289
Impact Factor 2.431
학술지명 Clinical cardiology.
서지사항 N집 / 39권 / 5호,   페이지(276 - 284)
요약초록문
(Abstract) 입력		 BACKGROUND:
Despite improved long-term safety of biodegradable polymer (BP) drug-eluting stents (DES) compared to first-generation durable polymer (DP) DES, data on the safety and efficacy of BP-DES compared with second-generation (2G) DP-DES in patients with acute myocardial infarction (AMI) are limited.
HYPOTHESIS:
To evaluate the safety and efficacy of BP-DES compared with 2G-DP-DES in the higher stent thrombosis (ST) risk setting of AMI.
METHODS:
A total of 3359 AMI patients who received either BP-DES (n = 261) or 2G-DP-DES (n = 3098) were included from the Korea Acute Myocardial Infarction Registry (KAMIR). Differences in baseline clinical and angiographic characteristics were adjusted using a 1:5 propensity score matching analysis (n = 261 for BP-DES and n = 1305 for 2G-DP-DES). The primary outcome was the incidence of major adverse cardiac events (MACE) including all-cause death, recurrent myocardial infarction (re-MI), and target vessel revascularization (TVR). The rate of definite or probable ST was also investigated.
RESULTS:
In adjusted analysis, there was no significant difference between the 2 groups in baseline clinical and angiographic characteristics; 2-year MACE (10.7% and 9.9% in the BP-DES group and 2G-DP-DES group, respectively, P = 0.679); ST incidence (0.8% vs 0.9%, respectively, P = 1.0), and rates of all-cause death, re-MI, and TVR. By multivariate analysis, old age, diabetes mellitus, renal dysfunction, and left ventricular dysfunction were the independent predictors of MACE after BP-DES or 2G-DP-DES implantation.
CONCLUSIONS:
BP-DES and 2G-DP-DES appear to have comparable 2-year safety and efficacy for the treatment of AMI. However, longer-term follow-up is needed.
파일  C184.Two-Year+Safety+and+Efficacy+of+Biodegradable+Polymer+Drug-Eluting+Stent+Versus+Second-Generation+Durable+Polymer+Drug-Eluting+Stent+in+Patients.pdf (212.3K) DATE : 2021-05-26 11:53:48