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논문번호 186
논문제목(영문) Long-Term Clinical Outcomes of Transient and Persistent No Reflow Phenomena following Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction.
국내외구분 국내 SCI여부 SCI(E)
연구책임자역할 공저자
주저자명 Kim MC
교신저자명 Ahn Y.
공동저자명 Kim MC, Cho JY, Jeong HC, Lee KH, Park KH, Sim DS, Yoon NS, Youn HJ, Kim KH, Hong YJ, Park HW, Kim JH, Jeong MH, Cho JG, Park JC, Seung KB, Chang K, Ahn Y.
게제년월일 2015-12-08
ISSN 1738-5520
Impact Factor 0.706
학술지명 Korean circulation journal.
서지사항 N집 / 46권 / 4호,   페이지(490 - 498)
요약초록문
(Abstract) 입력		 BACKGROUND AND OBJECTIVES:
There is limited information on the transient or persistent no reflow phenomenon in patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI).
SUBJECTS AND METHODS:
The study analyzed 4329 patients with AMI from a Korean multicenter registry who underwent PCI using coronary stents (2668 ST-elevation and 1661 non-ST-elevation myocardial infarction [MI] patients): 4071 patients without any no reflow, 213 with transient no reflow (no reflow with final thrombolysis in myocardial infarction [TIMI] flow grade 3), and 45 with persistent no reflow (no reflow with final TIMI flow grade≤2). The primary endpoint was all-cause mortality during 3-year follow-up. We also analyzed the incidence of cardiac mortality, non-fatal MI, re-hospitalization due to heart failure, target vessel revascularization, and stent thrombosis.
RESULTS:
The persistent no reflow group was associated with higher all-cause mortality (hazard ratio [HR] 1.98, 95% confidence interval [CI] 1.08-3.65, p=0.028) and cardiac mortality (HR 3.28, 95% CI 1.54-6.95, p=0.002) compared with the normal reflow group. Transient no reflow increased all-cause mortality only when compared with normal reflow group (HR 1.58, 95% CI 1.11-2.24, p=0.010). When comparing transient and persistent no reflow, persistent no reflow was associated with increased all-cause mortality (46.7 vs. 24.4%, log rank p=0.033).
CONCLUSION:
The persistent no reflow phenomenon was associated with a poor in-hospital outcome and increased long-term mortality mainly driven by increased cardiac mortality compared to the transient no reflow phenomenon or normal reflow.
파일  C186.Long-Term+Clinical+Outcomes+of+Transient+and+Persistent+No+Reflow+Phenomena+following+Percutaneous+Coronary+Intervention+in+Patients+with+Acute+Myocardial+Infarction..pdf (283.7K) DATE : 2021-05-26 11:54:57