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작성일 : 17-03-17 18:02
논문번호 192
논문제목(영문) Clinical impact of admission hyperglycemia on in-hospital mortality in acute myocardial infarction patients.
국내외구분 국외 SCI여부 SCI
연구책임자역할 교신저자
주저자명 Kim EJ
교신저자명 Jeong MH
공동저자명 Kim EJ, Jeong MH, Kim JH, Ahn TH, Seung KB, Oh DJ, Kim HS, Gwon HC, Seong IW, Hwang KK, Chae SC, Kim KB, Kim YJ, Cha KS, Oh SK, Chae JK; KAMIR-NIH registry investigators.
게제년월일 2017-01-13
ISSN 0167-5273
Impact Factor 4.638
학술지명 International journal of cardiology.
서지사항 N집 / 5273권 / 16호,   페이지(32921 - 32927)
요약초록문
(Abstract) 입력		 BACKGROUND:
Acute hyperglycemia on admission is common in acute myocardial infarction (AMI) patients regardless of diabetic status, and is known as one of prognostic factors. However, the effect of hyperglycemia on non-diabetic patients is still on debate.
METHODS:
A total of 12,625 AMI patients (64.0±12.6years, 26.1% female) who were enrolled in Korea Acute Myocardial Infarction Registry-National Institute of Health between November 2011 and December 2015, were classified into 4367 diabetes (65.4±11.6years, 30.4% female) and 8228 non-diabetes (63.3±13years, 23.9% female). Patients were analyzed for in-hospital clinical outcome according to admission hyperglycemic status.
RESULTS:
In diabetic patients, independent predictors of in-hospital mortality were old age, high HbA1C, pre-Thrombolysis In Myocardial Infarction (TIMI) flow 0, left ventricle ejection fraction<40%, cardiogenic shock and ventricular tachycardia. In non-diabetic patients, independent predictors of in-hospital mortality were old age, high admission glucose (≥200mg/dL), pre TIMI flow 0, failed percutaneous coronary intervention, low left ventricle ejection fraction<40%, cardiogenic shock, stent thrombosis and decreased Hb≥5g/dL. In hospital mortality was significantly higher in diabetic patients compared to non-diabetic patients (5.0% vs. 3.4%, p<0.001). However, non-diabetic patients with hyperglycemia have significantly higher mortality compared to diabetic patients (17.4% vs. 7.2%, p<0.001). Comorbidity including cardiogenic shock (p<0.001), cerebral hemorrhage (p=0.012), decreased Hb≥5g/dL (p=0.013), atrioventricular block (p<0.001) and ventricular tachycardia (p=0.007) was higher in non-diabetic with hyperglycemia than in diabetic patients.
CONCLUSIONS:
These findings underscore clinical significance of admission hyperglycemia on in-hospital mortality in non-diabetic AMI patients.
파일  C192.Clinical+impact+of+admission+hyperglycemia+on+in-hospital+mortality+in+acute+myocardial+infarction+patients. (1).pdf (514.3K) DATE : 2021-05-26 11:24:05