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논문번호 209
논문제목(영문) Comparison of short-term clinical outcomes between Resolute Onyx zotarolimus-eluting stents and everolimus-eluting stent in patients with acute myocardial infarction: Results from the Korea Acute Myocardial infarction Registry (KAMIR).
국내외구분 국외 SCI여부 SCI(E)
연구책임자역할 교신저자
주저자명 Kim Y, Oh SS
교신저자명 Jeong MH
공동저자명 Kim Y, Oh SS, Jeong MH, Ahn Y, Kim JH, Hong YJ, Sim DS, Kim MC, Kim HS, Yun KH, Oh SK, Kim CJ, Cho MC.
게제년월일 2018-05-10
ISSN 1897-5593
Impact Factor 1.256
학술지명 Cardiology journal
서지사항 0집 / 0권 / 0호,   페이지(0 - 0)
요약초록문
(Abstract) 입력
BACKGROUND:
There are few studies which compare the efficacy and safety of the Resolute Onyx zotarolimus-eluting stent (O-ZES) and everolimus-eluting stent (EES) in patients with acute myocardial infarction (AMI). Therefore, the present study aimed to compare clinical outcomes of O-ZES and EES in patients with AMI undergoing successful percutaneous coronary intervention (PCI).

METHODS:
From January 2016 to December 2016, the Korea Acute Myocardial Infarction Registry (KAMIR) enrolled 3,364 consecutive patients. Among them, O-ZES was used in 402 patients and EES was used in 1,084 patients. The primary endpoint was target lesion failure (TLF), as defined by composite of cardiac death, target vessel myocardial infarction (TV-MI), and ischemic driven-target lesion revascularization (ID-TLR) at six month clinical follow-up.

RESULTS:
At 6 months, the incidence of TLF was not significantly different between O-ZES and EES group (4.0% vs. 3.9%, adjusted hazard ratio [HR] 1.36, 95% confidential interval [CI] 0.67-2.77, p = 0.930). O-ZES also showed similar results of cardiac death (3.7% vs. 3.4%, adjusted HR 1.38, 95% CI 0.65-2.93, p = 0.771), TV-MI (0.2% vs. 0.6%, adjusted HR 0.86, 95% CI 0.09-7.90, p = 0.456), ID-TLR (0.0% vs. 0.3%, p = 0.524), and definite or probable stent thrombosis (0.2% vs. 0.3%, adjusted HR 1.71, 95% CI 0.06-46.09, p = 0.938) when compared with EES.

CONCLUSIONS:
The present study shows that implantation of O-ZES or EES provided similar clinical outcomes with similar risk at 6-month of TLF and definite/probable ST in patients with AMI undergoing successful PCI.
파일  C-209.pdf (2.5M) DATE : 2018-05-28 15:10:04