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논문번호 303
논문제목(영문) Predictors of Progression of Tricuspid Regurgitation in Patients with Persistent Atrial Fibrillation.
국내외구분 국내 SCI여부 KCI
연구책임자역할 공저자
주저자명 Song J
교신저자명 Cho JY, Kim KH
공동저자명 Choi GH, Lee N, Kim HY, Park H, Yoon HJ, Kim JH, Ahn Y, Jeong MH, Cho JG
게제년월일 2023-01-01
ISSN 2233-7385
Impact Factor 0
학술지명 Chonnam Med J
서지사항 0집 / 59권 / 1호,   페이지(70 - 75)
요약초록문
(Abstract) 입력		 Previous studies have shown that tricuspid regurgitation (TR) can be developed in patients with atrial fibrillation (AF) due to annular dilatation. This study aimed to investigate the incidence and predictors of the progression of TR in patients with persistent AF. A total of 397 patients (66.9±11.4 years, 247 men; 62.2%) with persistent AF were enrolled between 2006 and 2016 in a tertiary hospital, and 287 eligible patients with follow-up echocardiography were analyzed. They were divided into two groups according to TR progression (progression group [n=68, 70.1±10.7 years, 48.5% men] vs. non-progression group [n=219, 66.0±11.3 years, 64.8% men]). Among 287 patients in the analysis, 68 had worsening TR severity (23.7%). Patients in the TR progression group were older and more likely to be female. Patients with left ventricular ejection fraction <50% were less frequent in the progression group than those in the non-progression group (7.4% vs. 19.6%, p=0.018). Patients with mitral valve disease were more frequent in the progression group. Multivariate analysis with COX regression demonstrated independent predictors of TR progression, including left atrial (LA) diameter >54 mm (HR 4.85, 95%CI 2.23-10.57, p<0.001), E/e' (HR 1.05, 95%CI 1.01-1.10, p=0.027), and no use of antiarrhythmic agents (HR 2.20, 95%CI 1.03-4.72, p=0.041). In patients with persistent AF, worsening TR was not uncommon. The independent predictors of TR progression turned out to be greater LA diameter, higher E/e', and no use of antiarrhythmic agents.
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