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논문번호 73
논문제목(영문) Plaque prolapse after stent implantation in patients with acute myocardial infarction: an intravascular ultrasound analysis.
국내외구분 국외 SCI여부 SCI(E)
연구책임자역할 교신저자
주저자명 Hong YJ
교신저자명 Jeong MH
공동저자명 Hong YJ, Jeong MH, Ahn Y, Sim DS, Chung JW, Cho JS, Yoon NS, Yoon HJ, Moon JY, Kim KH, Park HW, Kim JH, Cho JG, Park JC, Kang JC;
게제년월일 2008-04-09
ISSN 1936-878X
Impact Factor 7.188
학술지명 JACC. Cardiovascular imaging
서지사항 0집 / 1권 / 4호,   페이지(489 - 497)
요약초록문
(Abstract) 입력		 OBJECTIVES:
The aim of this study was to assess the incidence, predictors, and outcome of plaque prolapse (PP) after stent implantation in acute myocardial infarction.
BACKGROUND:
The imaging characteristics of PP in patients with acute myocardial infarction are not well known.
METHODS:
Intravascular ultrasound (IVUS) imaging was performed in 310 patients immediately following stenting for their first acute myocardial infarction. Multiple clinical, angiographic and IVUS derived variables were compared among patients with and without intrastent PP.
RESULTS:
The PP was detected in 27% of the 310 lesions examined. Stent length was longer (31 +/- 13 mm vs. 21 +/- 8 mm, p < 0.001), and positive remodeling (48% vs. 32%, p = 0.008), plaque rupture (51% vs. 31%, p = 0.001), and thrombus (40% vs. 21%, p = 0.001) were significantly more common in PP lesions compared with non-PP lesions. The creatine kinase-myocardial band (CK-MB) was significantly greater after stenting in PP lesions compared with non-PP lesions (Delta = +12.3 +/- 32.0 U/l vs. -4.9 +/- 46.1 U/l, p = 0.002). During a 1-month follow-up, the incidence of stent thrombosis was not significantly different between PP and non-PP lesions [2/85 (2.4%) vs. 2/225 (0.9%), p = 0.308]. Multivariate analysis showed that PP (odds ratio [OR]: 7.34, p < 0.001), plaque rupture (OR: 1.95, p = 0.023), and thrombus (OR: 1.84, p = 0.026) were independently associated with post-stenting CK-MB elevation, and stent length (OR: 2.39, p = 0.003), plaque rupture (OR: 1.96, p = 0.015), and positive remodeling (OR: 1.72, p = 0.044) were independently associated with the development of PP.
CONCLUSIONS:
PP occurs in one-fourth of infarct-related arteries after stent implantation. Lesion characteristics such as plaque rupture and positive remodeling, together with longer stent predict PP. Although long-term follow-up is pending, PP is associated with more myonecrosis after stenting in patients with acute myocardial infarction.
파일  C73.+JACC+Cardiovasc+Imaging.+2008;1(4)489-497..pdf (193.9K) DATE : 2021-05-21 16:54:53