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논문번호 135
논문제목(영문) Coronary stent thrombosis: current insights into new drug-eluting stent designs.
국내외구분 국내 SCI여부 KCI
연구책임자역할 교신저자
주저자명 Kim HK
교신저자명 Jeong MH
공동저자명 Kim HK, Jeong MH.;
게제년월일 2012-10-26
ISSN 2233-7385
Impact Factor 0
학술지명 Chonnam Medical Journal
서지사항 0집 / 48권 / 3호,   페이지(141 - 149)
요약초록문
(Abstract) 입력		 Abstract: The advances of interventional cardiology have been achieved by new device development, finding appropriate drug regimes, and understanding of pathomechanism. Drug-eluting stents (DES) implantation with dual anti-platelet therapy reduced revascularization without increasing mortality or myocardial infarction compared with bare-metal stenting. However, late-term stent thrombosis (ST) and restenosis limited its value and raised the safety concern. Main mechanisms of this phenomenon are impaired endothelialization and hypersensitivity reaction with polymer. The second generation DES further improved safety and/or efficacy by using thinner stent strut and biocompatible polymer. Recently, new concept DES with biodegradable polymer, polymer-free and bioabsorbable scaffold are under investigation in the quest to minimize the risk of ST.
파일  C135.+Chonnam+Med+J.+2012;48(3)141-149..pdf (311.6K) DATE : 2021-05-26 09:50:53