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논문번호 51
논문제목(영문) Mechanical and Histopathological Comparison between Commercialized and Newly Designed Coronary Bare Metal Stents in a Porcine Coronary Restenosis Model.
국내외구분 국내 SCI여부 KCI
연구책임자역할 교신저자
주저자명 Lim KS
교신저자명 Jeong MH
공동저자명 Lim KS, Bae IH, Kim JH, Park DS, Kim JM, Kim JH, Sim DS, Hong YJ, Jeong MH;
게제년월일 2013-03-29
ISSN 2233-7393
Impact Factor 0
학술지명 Chonnam medical journal
서지사항 0집 / 49권 / 1호,   페이지(7 - 13)
요약초록문
(Abstract) 입력		 The aim of this study was to compare the stent designed by Chonnam National
University Hospital (designated as CNUH) with commercial cobalt-chromium coronary stent in a porcine coronary overstretch restenosis model. CNUH stent was subjected to mechanical performance tests. Pigs were randomized into two groups in which the coronary arteries (10 pigs, 10 coronaries in each group) had either CNUH stent or control commercial bare metal stent. Histopathologic analysis was assessed at 28 days after stenting. In mechanical performance tests, CNUH stent showed 2.65N, 35.1N, 0.52N, 1.94%, 4.29% in the flat plate radial compression, radial force, 3 point bending, Foreshortening and recoil test, respectively. There was no significant difference in the injury score, internal elastic lamina (IEL), lumen area, neointima area, percent area stenosis, inflammation score and fibrin score between the two groups (1.2±0.35, 4.1±0.41 mm(2), 2.7±0.56 mm(2), 1.6±0.47 mm(2), 36.7±11.2%, 1.2±0.62, 0.2±0.34 in CNUH stent group vs. 1.2±0.38, 3.7±0.64 mm(2), 2.5±0.49 mm(2), 1.5±0.61 mm(2), 36.3±12.17%, 1.1±0.12, 0.4±0.46 in commercial stent group, respectively). In the mechanical performance test, CNUH stent showed the moderated performance under the guideline of FDA. CNUH stent demonstrated similar histological reactions compared with commercial cobalt-chromium stent in a porcine coronary overstretch restenosis model.
파일  B51. Chonnam Med J. 2013;49(1)7-13..pdf (4.8M) DATE : 2016-03-13 10:16:24