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논문번호 106
논문제목(영문) Efects of a Titanium Dioxide Thin Film for Improving the Biocompatibility of Diamond‑Like Coated Coronary Stents
국내외구분 국외 SCI여부 SCI
연구책임자역할 교신저자
주저자명 Jae Won Shim
교신저자명 Myung Ho Jeong
공동저자명 Jae Won Shim, In‑Ho Bae, Myung Ho Jeong, Dae Sung Park, Kyung‑Seob Lim, Jae Un Kim, Mun‑Ki Kim, Jung Ha Kim, Ju Han Kim, Doo Sun Sim
게제년월일 2019-09-08
ISSN 2005-4149.
Impact Factor 1.99
학술지명 Metals and Materials International
서지사항 0집 / 26권 / 10호,   페이지(1455 - 1462)
요약초록문
(Abstract) 입력		 Abstract
This study was performed to evaluate the efects of a diamond-like carbon (DLC) layer on the biological properties of a pretreated titanium dioxide (TiO2) coronary stent surface. TiO2 and DLC were coated onto a cobalt-chromium stent surface in
consecutive order using the plasma-enhanced chemical vapor deposition method (TiO2/DLC). To investigate the efect of
TiO2, a group treated only with DLC was also prepared as a control. The surface characteristics were investigated by SEM,
ESCA, AFM, and contact angle analyses. To estimate the efect of surface modifcation on biological response, endothelial
cell migration was carried out. As a result, cracking of the coating layer on the strut curved portion in the DLC group was
restored in the TiO2/DLC group. ESCA result showed that the peaks sp2
and sp3
were slightly shifted and higher in the TiO2/
DLC group. The surface roughness average was highly increased in the TiO2/DLC group (Ra; 18.033) compared to the BMS
(Ra; 9.258) and DLC groups (Ra; 10.144). By the increment of Ra, the surface property became hydrophilic in the TiO2/
DLC group (39.8°±5.88°) compared to the non-treated (72.7°±2.24°) and DLC (78.6°±2.24°) groups. Endothelial cell
migration was signifcantly increased in the TiO2/DLC group (68.9±13.52%) compared to the non-treated (5.4±3.14%) and
DLC groups (22.3±8.22%). Therefore, the improvement of surface properties and endothelial cell migration in the TiO2/
DLC group could improve the physiological response in the human body.
파일  B106. Effects of a Titanium Dioxide Thin Film for Improving the Biocompatibility of Diamond-Like Coated Coronary Stents.pdf (2.0M) DATE : 2021-05-28 10:28:04