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논문번호 176
논문제목(영문) Comparison of the first- and second-generation limus-eluting stents for bifurcation lesions from a Korean multicenter registry.
국내외구분 국외 SCI여부 SCI(E)
연구책임자역할 공저자
주저자명 Cho Y
교신저자명 Kim HS
공동저자명 Cho Y, Koo BK, Song YB, Hahn JY, Choi SH, Gwon HC, Rha SW, Yu CW, Park JS, Bae JH, Lee JH, Jeong MH, Yoon JH, Jang Y, Kim HS;
게제년월일 2014-12-04
ISSN 1346-9843
Impact Factor 3.940
학술지명 Circulation journal
서지사항 0집 / 79권 / 3호,   페이지(544 - 552)
요약초록문
(Abstract) 입력		 BACKGROUND:
There are limited data on the relative efficacy of 1st- vs. 2nd-generation limus-eluting stents in bifurcation lesions. METHODS AND RESULTS: Our analysis of a Korean multicenter registry for bifurcated coronary lesions enrolled 1,762 patients treated with 2nd-generation everolimus-eluting stent (EES, n=348) or 1st-generation sirolimus-eluting stents (SES, n=1,414). In the overall population, EES was comparable to SES regarding major adverse cardiac events (MACE: composite of cardiac death, nonfatal myocardial infarction, and target vessel revascularization (TVR)), cardiac death, and TVR rates within a 2-year follow-up. In 1:3 propensity score-matched populations, EES showed a significantly lower MACE rate compared with SES (HR [95% CI], 0.53 [0.29-0.97]; P=0.039), mainly through a reduction in repeat revascularization (HR [95% CI], 0.47 [0.24-0.92]; P=0.027). EES was superior to SES in reducing TVR in patients with left main (LM) lesions (HR [95% CI], 0.21 [0.06-0.67]; P=0.008) or in patients treated with 2-stent technique PCI (HR [95% CI], 0.28 [0.09-0.91]; P=0.035). There was no difference in clinical outcomes between 2 stents in a non-LM bifurcation lesion or in patients treated with a 1-stent technique.
CONCLUSIONS:
At 2-year follow-up, 1st- and 2nd-generation limus-eluting stents showed comparable clinical outcomes in general bifurcation lesions. EES was superior to SES after matching by propensity score, especially in patients with LM bifurcation or in those treated by a 2-stent technique.
파일  C176.+Circ+J.+2015;79(3)544-552..pdf (1.2M) DATE : 2021-05-26 11:48:47